Vaskulitisi velikih krvnih žila

Jadranka Morović-Vergles, Silva Pukšić, Ana Gudelj Gračanin

Large vessel vasculitis includes Giant cell arteritis and Takayasu arteritis. Giant cell arteritis is the most commonform of vasculitis affect patients aged 50 years orover. The diagnosis should be considered in older patientswho present with new onset of headache, visual disturbance, polymyalgia rheumatica and/or fever unknown cause. Glucocorticoides remain the cornerstone of therapy. Takayasu arteritis is a chronic panarteritis of the aorta ant its major branches presenting commonly in young ages. Although all large arteries can be affected, the aorta, subclavian and carotid arteries are most commonly involved. Th e most common symptoms included upper extremity claudication, hypertension, pain over the carotid arteries (carotidynia), dizziness and visual disturbances. Early diagnosis and treatment has improved the outcome in patients with TA.

U vaskulitise velikih krvnih žila ubrajamo gigantocelularni i Takayasuov arteritis. Gigantocelularni arteritis najčešći je oblik vaskulitisa u odraslih na koji treba pomišljati u starijih osoba s novonastalom glavoboljom, poremećajima vida, polimijalgijom reumatikom i/ili vrućicom nejasnog uzroka. Glukokortikoidi su osnova liječenja. Takayasuov arteritis je kronični panarteritis aorte i njezinih glavnih grana koji se javlja u mladih osoba. Premda sve velike arterije mogu biti zahvaćene, najčešće su zahvaćene aorta, arterije subklavije i karotidne arterije. Najčešći simptomi su klaudikacije gornjih udova, hipertenzija, bol u području karotida (karotidinija), omaglice i poremećaji vida. Rana dijagnoza i liječenje značajno poboljšavaju ishod bolesti.