Complex regional pain syndrome - pathophysiology, clinical presentation and treatment
Authors:
Porin Perić
Summary
In 1994, a consensus group of experts gathered by the International Association for the Study of Pain (IASP) agreed on new diagnostic criteria for the reflex sympathetic dystrophy (RSD) and causalgia, and renamed them complex regional pain syndrome (CRPS) types I and II, respectively. CRPS is a complex pathophysiological entity characterised by pain, trophic and vasomotoric changes, limited function of affected body part and relatively fast development of osteoporosis of affected region. We described possible pathophysiological mechanisms which caused the pain, clinical presentation of the disease and tretment which includes all available pharmacological modalities as well as interventional procedures.
Sažetak
1994. godine skupina stručnjaka okupljena od strane Međunarodnog udruženja za proučavanje boli (eng. International Association for the Study of Pain - IASP) donijela je nove dijagnostičke kriterije za refleksnu simpatičku distrofi ju (RSD) i kauzalgiju i preimenovala ta stanja u kompleksni
regionalni bolni sindrom (KRBS), tip I i tip II. KRBS jest složeni patofiziološki entitet obilježen boli, oteklinom, trofičkim i vazomotornim promjenama, ograničenom funkcijom i relativno brzim razvojem osteoporoze zahvaćenog dijela. U radu su detaljno opisani mogući patofiziološki mehanizmi
nastanka boli, klinička slika i farmakološko liječenje uz intervencijske procedure.
