PRIKAZ BOLESNICE S VASKULITISOM TIJEKOM REUMATOIDNOG ARTRITISA

Domagoj Vergles, Ivana-Melanie Čulo, Željko Đuraševi, Dragica Soldo-Jureša, Krešimir Galešić, Jadranka Morović-Vergles

The presence of positive rheumatoid factor (RF) titer in a patient with rheumatoid arthritis (RA) is of clinical value because its presence tends to correlate with the development of extraarticular manifestations. There is a loose correlation with severity of disease and titer. Extraarticular manifestations includes vasculitis, pericarditis, subcutaneous nodules, pulmonary nodules or interstitial fibrosis, episcleritis and mononeuritis multiplex. The vasculitis is most frequently evidenced as skin infarctions/ulcerations and mononeuritis multiplex. We report a case of rheumatoid vasculitis in a 48 years old women with long history of RA, who developed vasculitis of distal arteries with gangrene of digits of upper and lower extremities.

Nalaz reumatoidnog faktora (RF) u bolesnika s reumatoidnim artritisom (RA) od kliničkog je značaja jer se u tih bolesnika češće javljaju izvanzglobne manifestacije bolesti. U izvanzglobne manifestacije ubrajamo: vaskulitis, perikarditis, potkožne čvoriće, čvoriće na plućima ili intersticijsku fibrozu pluća, episkleritis i mononeuritis multiplex. Vaskulitis se klinički najčešće očituje infarktima i/ili ulceracijama na koži te kao mononeuritis multiplex. U radu smo prikazali 48 godišnju bolesnicu s anamnestičkim podatkom o višegodišnjem RA i razvojem vaskulitisa distalnih arterija s gangrenom prstiju šaka i stopala.