MELOXICAM - THE BALANCE OF EFFICACY AND SAFETY
Authors:
Jadranka Morović-Vergles
Summary
NSAIDs remain the principal pharmacological agents used for symptom relief in patients with rheumatic disease. They represent the largest single group of drugs used worldwide. Given the large number of available NSAIDs, it is unsurprising that some differences exist among them with regard to mechanism of action, pharmacokinetics, and tolerability. How these differences affect the overall risks and benefits of treatment continues to be examined in clinical trials. Meloxicam is COX-2 selective NSAID with favourable gastrointestinal and thromboembolic safety profile.
Sažetak
Nesteroidni antireumatici (NSAR) osnovni su lijekovi koji se rabe za suzbijanje boli, upale i snižavanje tjelesne temperature. NSAR su velika heterogena skupina lijekova, često kemijski nisu srodni, ali su sličnog učinka i nuspojava. Meloksikam je selektivni COX-2 inhibitor, povoljnog gastrointestinalnog i tromboemboličkog sigurnosnog profila.
