EXTRASKELETAL MANIFESTATIONS OF SERONEGATIVE SPONDYLOARTHROPATHIE
Authors:
Jadranka Morović-Vergles
Summary
Spondyloarthropathies constitute a cluster of interrelated and overlapping chronic inflammatory rheumatic diseases of unknown etiology that include ankylosing spondylitis, psoriatic arthritis, reactive arthritis, enteropathic arthritis and undifferentiated spondyloarthritis. These diseases are not associated with rheumatoid factor, they occur in genetically predisposed individuals and show a strong association with HLA-B27. The primary pathologic sites include the entheses, the sacroiliac joints and the axial skeleton with or without some nonarticular structures, such as the skin, eye, aortic valve, heart and kidney.
Sažetak
Seronegativne spondiloartropatije (SS) skupina su upalnih reumatskih bolesti nepoznatog uzroka u koje ubrajamo ankilozantni spondilitis, psorijatični artritis, reaktivni artritis, enteropatski artritis i nediferenciranu spondiloartropatiju. Zajedničko im je obilježje odsustvo reumatoidnog faktora u krvi, česta pojavnost bolesti među bliskim srodnicima i visoka zastupljenost HLA B27 antigena među bolesnicima. Klinička obilježja SS jesu periferni artritis, zahvaćenost kralježnice i sakroilijakalnih zglobova te tetivnih hvatišta s ili bez izvankoštanih obilježja tj. promjena na koži, sluznicama, aorti, srcu, očima i bubrezima.
